Posts

Showing posts from August, 2013

Asthma-Autism Hypothesis and Immunomodulatory Therapy for Autism

Image
You may be aware that about a third of people with autism also have asthma; this is not a coincidence, just as the finding that autistic people have elevated cholesterol was not a coincidence.   Since Monty, aged 10,   has both autism and asthma, I have had to become informed on both conditions.   Having now read the research on both autism and asthma, it is somewhat shocking that there are so   many parallels.   I would now go so far as to make my own hypothesis:- The causes of Autism and Asthma are overlapping; so much so, that some drug treatments for the core symptoms of one may be effective in the other. This may sound a strange, even bizarre proposition, but I will show that it is at worst plausible and at best proven.   Note that it was the observation that bumetanide was an effective treatment in neonatal non-convulsive seizures ,that led to the idea of trialling that drug on autistic children.   Many children with autism subsequently develop e...

Potassium may play an important role in Autistic Behaviours

This is not the kind of post that I expected to be writing.   How can the effect of something so simple as a mineral, not have been noticed by others and researched in depth? Potassium (K + ),   is one of several electrolytes that occur in humans, the others being sodium(Na + ), calcium (Ca 2+ ), magnesium (Mg 2+ ), chloride (Cl − ), hydrogen phosphate (HPO 4 2− ), and hydrogen carbonate (HCO 3 ) Electrolyte balance or homeostasis is regulated by specific hormones.   These electrolytes are used to control many aspects of your body.   The concentration of each electrolyte varies across the boundary of each cell.   Electrolytes pass through the cell wall/membrane through so called ion channels.   These are like special valves that open and close based on particular pre-programmed circumstances.   When these ion channels malfunction, often due to a genetic fault, disease occurs.   Ion channel diseases have a special name - channelopathies.   T...