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How much Histidine? Dermatitis and FLG mutations

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Today’s post is not about autism, it is about allergy and atopic dermatitis in particular. Many people are affected by atopic dermatitis (AD), also known as eczema; it is particularly common in those with autism. Children who develop asthma have often first developed atopic dermatitis (AD). Atopic Dermatitis is another of those auto-immune conditions and the sooner you stabilize such conditions the better the prognosis. Skin therapies from a company spun-off from Manchester University Histidine A while back on this blog I was looking at the various amino acids and came across the observation that histidine, a precursor of histamine, appears to be a mast cell stabilizer. Mast cells are the ones that release histamine and IL-6 into your blood. Histamine then does on the trigger yet more IL-6 to be produced.   IL-6 is a particularly troublesome pro-inflammatory cytokine. At first sight giving a precursor of histamine to people who want less histamine seems a crazy thing to do, but ple...