Ginseng, as a GABAb Antagonist, as an "Add-on Therapy" for some Autism? Also Homotaurine and Acamprosate
Rather like negotiating with North Korea, today’s post does rather meander. It does in the end up with some interesting options for some people. Korea - the centre of Ginseng research This post was prompted by research highlighted by our reader Ling, which suggested that bumetanide responders (i.e. people with high intracellular chloride) might benefit from a GABA B ant agonist. There has been quite a lot of coverage in this blog about agonists of GABA B receptors, like Baclofen and Arbaclofen. Some people with an autism diagnosis do indeed seem to benefit, ranging from some with Fragile-X to others with Asperger’s. Russian-developed GABA B agonists like Phenibut and Pantogam are widely used by adults self-treating their behavioural/emotional disturbances. Some Aspies have commented in this blog that far from helping, Baclofen made them feel worse; perhaps the opposite therapy might help? (the Goldilocks scenario, from the previous post) The paper below shows how a G...