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Showing posts with the label Selenium

Refining Antioxidant (ROS & RNS) Therapy in Autism -  Selenium and Molybdenum

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Today’s post is about further refining antioxidant therapy. As we saw in a recent post, oxidative and nitrosative stress is a very common feature of autism and is treatable with OTC products. The cheapest antioxidant, N-acetylcysteine (NAC), looks to be the best one, but there are numerous others with exotic names and equally   exotic prices. Today we just look at selenium and molybdenum.   Selenium was on my to-do list for a long time because it affects some key enzymes call GP X (glutathione peroxodases). Molybdenum was enthusiastically recommended in a recent comment and this blog has previously touched on Molybdenum Cofactor Sulfurase (MOCOS). Rather surprisingly, there is a commercial product that contains NAC, Selenium and Molybdenum.   Selenium and GP X (glutathione peroxodases) There are eight different glutathione peroxodases , but GPx1 , GPx2 , GPx3, and GPx4 are all made from selenium. GP X speeds up the antioxidant reactions that involve glutathione (...

Why not Cocoa Flavanols for Autism?

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    Judging by my blog statistics, lots of people are interested in broccoli (Sulforaphane) to treat autism.  Thanks to the patents held by Johns Hopkins, you can expect to hear much more about Sulforaphane in the coming years. Meanwhile, Columbia University and Mars, the chocolate people, have released a study showing that “ flavanoids ” in cocoa can do wonders for memory loss in older people.  In effect, they can restore memory in 60 years olds to where it was 20 or 30 years earlier. If you take a step back and look at what is known by science about oxidative stress and antioxidants, all will become much clearer. Oxidative Stress Pioneers In an earlier post we met Paul Talalay, a German-American, who worked at Johns Hopkins.  He specializes in foods that protect you from cancer.  He is Mr Broccoli.  It turns out that perhaps the real pioneer in this field is a 100% German, called Helmut Sies, who also studies foods that act as antioxidants and nutrie...