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Showing posts with the label Colonic

Ketones and Autism Part 3 - Niacin Receptor HCA2/GPR109A in Autism, Colonic Inflammation, Psoriasis and Multiple Sclerosis

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  Repurposing a German psoriasis treatment for the second time? First for Multiple Sclerosis and second for some Autism? Today’s post is about one anti-inflammatory aspect of ketones; part 4 in this series will look at Ketones and their effect on the NLRP3 inflammasome, which also relates to inflammation; but it would be too much for one post. If you have elevated levels of the inflammatory cytokine IL-1β, common in much autism and Alzheimer’s, part 4 of this series will be very relevant. Today we just look at HCA2, which should be interesting for people with Multiple Sclerosis (MS), psoriasis and anyone with autism who responds to HCA2 activation. In Germany a tailor-made solution already exists for a potential clinical trial to evaluate the effect of HCA2 activation; and even with low dose tablets. Activating HCA2 should have profound neuroprotective effects; the ways to activate it include: - ·         BHB ( β-hydroxybutyrate ) from the ketogen...