PLT Test Blog

  Adult-sized people with autism can cause property damage and much worse. I am told that summertime raging is a common problem encountered by neurologists, but it remains poorly understood and usually remains untreated. The most common worry for parents of toddlers diagnosed with severe autism is their lack of speech. By the time these children reach adulthood, the biggest worry for parents is often aggression and self-injury. Often it is the mother who faces the worst episodes of aggression, which is a really cruel turn of events. Aggression is usually not present in young children with autism, in some people it never develops, but in others it later becomes established as a learned behavior and then you are stuck with how to deal with it. One of my own therapy targets has long been to improve cognitive function; this can indeed be achieved and then you can improve important daily living skills (adaptive function). Some steps that you can take to improve cognition, and indee...

By far the most read post in this blog is one about histamine and allergies, which means many people are searching on Google for “histamine, allergy and autism”. Our reader Kei recently commented that his daughter, without allergy, was again showing signs of summertime raging and that his neurologist confirmed that summertime raging does indeed happen and nobody knows why. I did figure out how to deal with our version of “summertime raging” and the post-bumetanide “dumber in the summer” phenomena.   There were several posts on this subject.   The lasting solution was to treat the raging as if it was caused by inflammation driven by pollen allergy and to note that inflammation will further worsen the KCC2/NKCC1 imbalance in Bumetanide-responsive autism, making those people appear “dumber in the summer”.   This also accounts for the “Bumetanide has stopped working” phenomenon, reported by some parents.   You need to minimize inflammation from allergy and increase Bumet...

When I first connected histamine to autism, I did not realize that this might be a common problem.   The most frequently viewed post on this blog is one on histamine and autism; so at least 10,000 people out there have googled “autism and histamine”. Two years later, the therapy is still evolving and it should be said that, what works best for one person may not help in another person.  The main point is that in some people with autism, they face a summertime regression due to the effect of allergy.  So bad behaviours and aggression increase and good behaviours and indeed cognitive function decrease.  This appears to be the result of histamine and a pro-inflammatory cytokine called IL-6. For the 2015 pollen season, which started early where we live, this is what we are using:- Azelastine nasal spray, this is an H1 antihistamine that is also inhibits mast cells from “degranulating” and emptying their load of pro-inflammatory substances.  Once a day. Quercetin i...