PLT Test Blog

  Results from the PaxMedica trial of Suramin For me, Bumetanide for Autism is now ten-year-old news, for us it has been working since 2012; the next interesting drugs in the pipeline include Suramin and Leucovorin. It is extremely difficult to trial Suramin at home, or indeed anywhere, and this makes it ever more desirable to many parents. Leucovorin (calcium folinate) is easy to obtain; you can even buy liquid calcium folinate from iHerb.   You can find out pretty quickly if it produces a profound benefit on your child’s type of autism. I wish Dr Frye and Professor Ramaekers good luck with the phase 3 trial of Leucovorin.   It certainly works for our adult reader Roger, but not for my 18 year old son, Monty.   Our reader SB’s child recently joined the group of confirmed responders. After I started writing this post, the results came in of a large (250 children) trial of intranasal oxytocin.   This trial failed to show any benefit, over the placebo, in inc...

    For leaky ATP, Popeye might want to try Dexpramipexole and Suramin, or even the already approved Mirapex If you are old enough to be a parent, you will have encountered problems with some kind of leak.  A leaky roof, a leaky pipe, a leaky washing machine, an air-conditioning unit... The list goes on, the older you get. I have been preoccupied by fixing a leak recently.   We have a large roof terrace and, in the winter, water started leaking from the ceiling in the floor below.   I improvised a system to catch all the water, but still I had to find the source of the leak. I did finally find the source of the problem and most importantly without digging up 95% of the terrace.   Now I have to put the 5% back together again. Leaks are often extremely difficult to locate, because water always finds the easiest path and the dripping you see might have originated from a leak far away.   Nobody wants to fix leaks, because it can be a pretty thankle...

The new Chinese and old Colonial, side by side in central Shanghai     I do not speak Chinese, but fortunately Google does. I was sent some interesting links to some articles from China about Suramin, the potential autism therapy which many autism parents are eagerly awaiting.   Prepare for a long wait, but hopefully less long in China. My original post on Suramin for autism can be found  in the link below:- Suramin, the Purinome and Autism     I have never had a banner appear on my computer trying to sell me a Rolls Royce until today.   This is more proof, if I needed it, of how much China has changed since my first visit there as a teenager.   Back then there were a lot of bicycles; I still remember many were Flying Pigeon brand – not a name you forget. I just looked them up and since 1950, more than 500 million Flying Pigeon bicycles have been made - that is a lot bicycles. I even went to see a factory still producing steam locomotives ...