PLT Test Blog

Photobiomodulation underlying mechanisms at the cellular and molecular levels. Light at 600–850 nm is absorbed by the mitochondrial electron transfer chain and leads to upregulation of the neuronal respiratory capacity . The near-infrared light at range of 900– 1100 nm is absorbed by structured water clusters formed in or on a heat/light-gated ion channels . An increase in vibrational energy of water cluster leads to perturb the protein structure and opening the channel which ultimately allows modulation of intracellular Ca2+ levels. The absorption of green light by neuronal opsin photoreceptors (OPN2-5) activates transient receptor potential channels which causes nonselective permeabilization to Ca2+ , Na+ , and Mg2+ . The cryptochromes (a class of flavoprotein blue-light signaling receptors) absorb blue light and seems to activate the transducing cellular signals via part of the optic nerve to the suprachiasmatic nucleus in the brain, which is important in regulation of the circadian...

Today’s post is all about one of the potential medical, but non-drug, interventions for autism. The others tend to involve electrical/magnetic stimulation of one kind or another. Low level laser therapy (LLLT) was developed more than fifty years ago in Russia. Today in Western countries LLLT is often regarded as alternative medicine or just quackery.   There are some FDA approved devices.   In Russia and some East European countries LLLT is part of mainstream medicine. Two people forwarded me a recent study that was carried out in Havana by a team from Cuba and Israel. There are only 11 million Cubans, but there are a lot of Cuban doctors.   They have developed interesting drugs, some related to cancer, that are now being taken up by Western medicine.   Cuba actually leases out doctors to work in more than 50 developing countries around the world. The results of the study are indeed interesting and there is a long list of possible mechanisms that may be involved. The...