PLT Test Blog

Today’s post is about further refining antioxidant therapy. As we saw in a recent post, oxidative and nitrosative stress is a very common feature of autism and is treatable with OTC products. The cheapest antioxidant, N-acetylcysteine (NAC), looks to be the best one, but there are numerous others with exotic names and equally   exotic prices. Today we just look at selenium and molybdenum.   Selenium was on my to-do list for a long time because it affects some key enzymes call GP X (glutathione peroxodases). Molybdenum was enthusiastically recommended in a recent comment and this blog has previously touched on Molybdenum Cofactor Sulfurase (MOCOS). Rather surprisingly, there is a commercial product that contains NAC, Selenium and Molybdenum.   Selenium and GP X (glutathione peroxodases) There are eight different glutathione peroxodases , but GPx1 , GPx2 , GPx3, and GPx4 are all made from selenium. GP X speeds up the antioxidant reactions that involve glutathione (...

The original idea of this blog was to try to keep complicated things as simple as possible, so at times things may get over-simplified.   This post starts out simple and then gets rather involved in oxidative stress. When people think about genes, they are nearly always thinking about the “blueprints” that are encoded on your DNA.  As it turns out only about 5% of your DNA is dedicated to this function; this 5% is contained in the exome . Much autism research is dedicated to finding faulty “blueprints” that might account for autism.   There are now several hundred so called “autism genes”, where an error in the “blueprints”, means that the associated protein is not produced to its intended specification. We also have seen that genetic defects just lead to a possibility of something going wrong.  A “faulty gene” creates the possibility of a specific dysfunction happening, it does not mean 100% that it will happen.  Partial dysfunctions and partial deficiency...