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Showing posts with the label Basal Ganglia

Autism + PANDAS/PANS ? - Basal ganglia circuitry mechanism underlying some repetitive behaviour

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Pu-erh, a fermented tea from Yunnan province, China.   An mGluR5 inhibitor to remedy basal ganglia circuit abnormalities? PANDAS / PANS ( Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections/ Pediatric Acute-onset Neuropsychiatric Syndrome) are recognized disorders in North America, but nowhere else.   If you take your child to Boston Children’s Hospital and ask about PANDAS they will know what you are talking about, try this at a children’s hospital in Europe and you will be directed to the local zoo. For those new to the subject PANDAS / PANS cause sudden onset of tics and Obsessive Compulsive Disorder (OCD) accompanied by sudden cognitive regression. I have written about PANDAS/PANS in previous posts. PANDAS, PANS, Penguins and Autism I was surprised how well documented these syndromes are and that they are treated by some mainstream physicians. The leading researcher in the field, Susan Swedo, makes a point that PANDAS/PANS is not aut...