PLT Test Blog

  Nestle’s research centre in Lausanne, Switzerland I did write extensively about the potential to treat some autism using the ketone BHB (beta hydroxybutyrate). This can be achieved either by following a strict ketogenic diet or just by eating medical foods that contain/produce BHB. Some readers are now big consumers of BHB supplements and anyone taking BHB should be interested in today’s paper, that I assume was paid for by Nestlé. Nestlé make everything from baby milk formula to George Clooney’s Nespresso.   You may not be aware that they also have a business selling medical food; they have been looking at ketones to treat Alzheimer’s for some time.   This is quite similar to Mars developing Cocoa flavanols to improve heart and brain health. Most ketone supplements are sold to help you lose weight or boost athletic performance.   The military also uses ketones in survival rations.   We saw that you can increase the level of ketones in your body by supplementi...

The potential benefit of the ketone BHB in autism was covered extensively in earlier posts.   It looks like different people may benefit for entirely different reasons and some may not benefit at all.  Some MCT oils, taken as precursors to BHB, can actually make people worse. Measuring ketones and glucose in blood Click for a summary of the previous posts. Ketone Therapy in Autism (Summary of Parts 1-6) I know that some readers of this blog have found that BHB/C8 does indeed provide a benefit in their specific type of autism.   The benefit seems to vary, but given all the biological modes of action of the ketone BHB that is not surprising.   Increased speech is a frequently noted benefit. My initial combination of Ketoforce plus C8 continues to be effective. Substituting a cheaper MCT oil containing both C8 and C10 (Bulletproof XCT oil), was less effective and after a matter of weeks produced a negative effect. It appears that C10, after a while, can produce mild anx...

Open the above file via Google Drive, so it is big enough to read. Click the link below. You can also take links from it to the relevant blog post. https://drive.google.com/file/d/1Jl_JMUrX7suXz0n_yJPCLPinrvdddBhI/view?usp=sharing In the mini series of posts on ketones and autism we have come across a long list of effects that will benefit certain groups of people. 1.      Change in gut Bacteria 2.      Ketones as a brain fuel      3.      Niacin Receptor HCA2/ GPR109A 4.      NAD sparing 5.      CtBP Activation by reducing NADH/NAD+ ratio 6.      NLRP3 Inflammasome inhibition 7.      Class 1 HDAC inhibition 8.      Increase BDNF 9.      Ramification of Microglia 10. PKA activation 11. PPAR gamma activation It was interesting that the beneficial effect of the Ketogenic Diet in epilepsy i...