From PANS to PANDAS? Another Problem Solved
Source: EpiphanyASD There is a lot written about PANS (Pediatric Acute-onset Neuropsychiatric Syndrome) and PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) which is a subset of PANS; however they are still not fully recognized as medical conditions. I prefer to see PANS/PANDAS in the broader context of autoimmune encephalitis, a collection of related conditions in which the body's immune system mistakenly attacks the brain, causing inflammation. The immune system produces antibodies that mistakenly attack heathy receptors in the brain. Depending on which types of receptors are targeted, you will get different symptoms, plus you will get symptoms from the inflammation. If they are NMDA receptors, you may have hallucinations and appear to have developed schizophrenia overnight. It has been suggested that the definition of PANS is too narrow and a broader term called CANS was proposed. CANS is not exactl...