PLT Test Blog

  Repurposing a German psoriasis treatment for the second time? First for Multiple Sclerosis and second for some Autism? Today’s post is about one anti-inflammatory aspect of ketones; part 4 in this series will look at Ketones and their effect on the NLRP3 inflammasome, which also relates to inflammation; but it would be too much for one post. If you have elevated levels of the inflammatory cytokine IL-1β, common in much autism and Alzheimer’s, part 4 of this series will be very relevant. Today we just look at HCA2, which should be interesting for people with Multiple Sclerosis (MS), psoriasis and anyone with autism who responds to HCA2 activation. In Germany a tailor-made solution already exists for a potential clinical trial to evaluate the effect of HCA2 activation; and even with low dose tablets. Activating HCA2 should have profound neuroprotective effects; the ways to activate it include: - ·         BHB ( β-hydroxybutyrate ) from the ketogen...

Far back in this blog, I wrote a post about fish oil.   Omega 3 oils are definitely good for your general health, but do they help with autism?   They are also claimed to help with ADHD and improve your NT child’s cognitive performance. On critical review of the evidence, it seemed that the benefit was far from conclusive.  There was one very positive study, that neither the authors nor anyone else could repeat. The following review of the literature by the University of Maryland show that, as with autism, studies on fish oil in depression, ADHD, bipolar and schizophrenia show conflicting results. Omega-3 fatty acids Some of the “cognitive enhancing” fish oil products are extremely expensive and I showed that regular fish consumption was far cheaper and likely to be as effective. There is an issue of just how big an effect you are looking for.  We can all imagine tiny effects, but you really want an effect that everyone else notices. Monty, aged 11 with ASD, eats lo...