Posts

Showing posts with the label Sulforaphane

The Kynurenine Pathway in Autism and its modification using Sulforaphane or the probiotic Lactobacillus Plantarum 299v

Image
    A pathway to somewhere, hopefully Today’s post was prompted by our reader George’s observation that the probiotic Lactobacillus Plantarum 299v increased speech in his adult son.   This widely available probiotic is commonly used to treat IBS (Irritable Bowel Syndrome) and I did mention it in a recent post about Eubiotics. Eubiotics for GI Dysfunction and some Autism Increased speech is a target for many people treating autism and this probiotic is known to be safely used long term - so it is interesting. Since I already had this probiotic at home, I made a trial and I observed a very similar effect to what happened several years ago when Monty started to use Sulforaphane / broccoli sprout powder.   The effect of broccoli powder was a brief period of euphoria about 20 minutes later and a then a marked increase in verbalization.   The effect on mood was seen by some other readers, but not the majority. I recall back then a very happy parent who was feedin...

2021 Autism PollyPill To Do List – Speech ↑ and Misophonia ↓

Image
    A few ideas remain to be fine-tuned Having started to develop my son’s polytherapy for autism back in December 2012, is there anything left to develop in 2021? As we have seen, the biggest impact from interventions is when you start them very young, but improvement is possible at any age. I was asked at the recent Synchrony autism conference what is next for the PolyPill?   and I replied that more spontaneous expressive language is my main target.   I have a good idea of what may help. ·         Calcium folinate, increased over 6 weeks to 45mg/day ·         Sulforaphane, with added Myrosinase in the form of Wasabi I was contacted by a researcher from that Synchrony conference, suggesting that Low Level LED Therapy (LLLT) was worth trying to improve the use of speech.   It does seem to benefit people with many types of brain injury.   I did write a post on LLLT using lasers,...