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Showing posts with the label Autonomic

The Autonomic Nervous System (ANS), Heart Rate Variability (HRV), Performance Anxiety, Propranolol, Vagus Nerve Stimulation and Autism

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Performance anxiety symptoms may include: ·        Racing pulse and rapid breathing. ·        Dry mouth and tight throat. ·        Trembling hands, lips, and voice. ·        Sweaty and cold hands. ·        Nausea  ·        Vision changes. Today’s post started out to be all about Propranolol, a very old and widely prescribed drug that lowers your blood pressure, but does other interesting things as well. It is used to treat several psychiatric disorders and has been widely trialled in autism. As I started researching I decided to broaden the post to bring in Heart Rate Variability (HRV), which one reader of this blog suggested as a useful measure of the effect of supplements.    HRV is actually a good indicator of a dysfunction in the Autonomic Nervous System (ANS).  The Autonomic Nervous Sy...

“Spray Fire in my Head” and how putting it out with Verapamil links Histamine, IL6, Mast cells, Calcium Channel Cav1.2, and even the Vagus Nerve

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After 18 months of researching autism, things are falling nicely into place.   For regular readers of this blog, it may seem that we have uncovered a bewildering number of issues/dysfunctions that need to be addressed by the science.   In fact, when you look closer still, you will see that many of these issues are interrelated and you do not need to treat each one.   Also, it is clear that many different methods can be used to treat the same dysfunction.   The best methods though would be the simplest, safest, cheapest and the ones that address multiple issues at once. One such little gem is Verapamil, an extremely cheap calcium channel blocker that has been widely used for 30 years for other conditions.  Spray Fire in my Head Monty, aged 10 with ASD, suffers from allergies like many children.  I noticed that his pollen allergy provoked a dramatic increase in his autistic behaviors.  Last year I spent time developing a treatment for these summertime au...