Metformin to raise Cognition in Fragile X and some other Autisms?
I started to write this post a long time ago, when Agnieszka first highlighted an interview with Dr Hagerman from UC Davis. Hagerman is experimenting in using Metformin to treat Fragile-X. Having again be reminded about Metformin, I realized that I never finished my post on this subject. With some extras about autophagy and a nice graphic courtesy of Ling’s excellent paper, here it is. Metformin has already been covered in 5 previous posts. https://epiphanyasd.blogspot.com/search/label/metformin One interesting point is that the researchers at UC Davis are using the measurement of IQ as one of the outcome measures in their trial of Metformin. I have been suggesting the French Bumetanide researchers do this for a long time. It is my opinion that simple medical interventions can have a profound impact on the IQ of some people with severe autism. I mean raising IQ not by 5-10 points as at UC Davis, but by 20-50 points. IQ can be measured using standardized tools ...