PLT Test Blog

  That alternative world, where you fix things when they are not working I do sometimes forget the world that most people live in, when it comes to (not) understanding and (not) treating autism. I decided to write this post on lethargy and autism, after being prompted by a friend who contacted me and told me that his son with autism is very lethargic (physically and mentally). I replied with the suggestion that he try a little scoop of Agmatine Sulphate.   Now his son is able to go for long walks, without constantly wanting to stop for a rest.   The Dad asked me to share his positive experience with Agmatine. A few years ago, this boy was diagnosed by Dr Kelley with mitochondrial dysfunction.   People with mitochondrial dysfunction should indeed have poor exercise endurance, this is because they lack the enzymes needed in a process called oxidative phosphorylation (OXPHOS).   OXPHOS is the metabolic pathway in which cells use enzymes to oxidize nutrients, ther...

Yet more money was just donated to autism research. In 2017 the CEO of Broadcom gave $20 million to MIT and now he has given $20 million to Harvard, where he did his MBA. Time to boost Homer's mitochondria? I think philanthropists from the fast-moving IT sector should demand rather more from the slow-moving world of autism research.   I also think common sense is often more lacking than money. The US Government has also just announced $1.8 billion for autism research. Donald Trump authorized a five-year extension of the Autism Collaboration, Accountability, Research, Education and Support (CARES) Act. The 2014 act dedicated funds to children with autism spectrum disorder, but the new version includes adults.   Children with autism do indeed grow up to become adults with autism.   Today we look at further applications of DMF, which is a cheap chemical also sold as a very expensive drug. We learnt from Dr Kelley, from Johns Hopkins, that most regressive autism features mito...

Today’s post was originally intended to look at some further methods used to enhance cognitive function. Unlike people with typical mild cognitive impairment (MCI), some people with autism exhibit highly variable cognitive function, one way this is visible is in their hand writing quality. We previously saw that in cases of PANDAS/PANS, deterioration of hand writing is also seen during acute episodes.   One possible cause of cognitive decline is mitochondrial dysfunction.   This is a highly complex subject in its own right and so I decided to start with a post introducing mitochondrial disease and dysfunction.     Mitochondria Mitochondria are tiny organelles found in almost every cell in the body. These organelles are responsible for creating 90% of cellular energy necessary to maintain life and support growth. Mitochondrial disease occurs when mitochondria in the cells fail to produce enough energy to sustain cell life. When enough cells cease to function properly ...