PLT Test Blog

Sulfarlem has been used to treat dry mouths for half a century By www.scientificanimations.com - http://www.scientificanimations.com/wiki-images/, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=77499374 Sulfarlem is a drug containing a chemical called Anethole trithione . Anethole is an organic compound used as a flavouring, i t contributes a large component of the odour and flavour of anise and fennel. Anise seed, or aniseed, contains a large amount of Anethole. The popular Greek drink Ouzo turns cloudy when diluted with water because of the Anethole. For the French it is called Pastis.                                                                  ...

In my book I will be covering the science behind hopefully almost all autism, which then naturally leads to translating it into therapy.  In the ideal world you would just skip straight to the therapy and the final section of the book will be just that.  Clearly it would make sense to read the science first, so that you know what are the dysfunctions that you might need to treat. Hopefully there will also be some case studies from people who have applied a science-based approach to identify and implement effective therapies. Roger would clearly make a very good example of a reversible in-born metabolic-caused type of autism. I will be posting on my blog some drafts from the Part III - Translating Science to Treat Autism.  This is of course just one person's collection of other people's ideas and some of his one.  The reader and his/her medical medical team ultimately decide what to implement and must monitor its ongoing implementation.  * * *...

This blog is mainly about classic early-onset autism and the biology underlying it. There are many other disorders that also result in autistic behaviours, some of which are much better understood than classic autism.  Today’s post is about Mitochondrial Disease which appears to be the precursor to most cases of regressive autism, according to Dr Richard Kelley, at Johns Hopkins and the Kennedy Krieger Institute. In well-resourced centers for autism, by which I mean large teaching hospitals in the US, cases of autism are often fully investigated.  First they rule out mitochondrial disease and common known single gene causes like Fragile X.  Next comes the chromosome microarray. The microarray (often referred to as CMA) may identify a genetic cause in 15-20% of individuals with an ASD.  In the rest of the world no such testing takes place, unless you are very lucky. If the supplement Carnitine makes you feel better, read on, because you quite likely have some mitocho...