Glass Syndrome / SATB2-associated syndrome – Osteoporosis and ERβ
The world’s longest glass bridge is in China. Today’s post is about Glass Syndrome / SATB2-associated syndrome, it occurs when something goes wrong with a gene called SATB2; there are several variants because different mutations in this gene are possible. Glass Syndrome / SATB2-associated syndrome is another of those single gene types of autism, so you can think of SATB2 as another autism gene. As we will see in today’s post SATB2 is involved in much more than autism and is very relevant to osteoporosis and some types of cancer. While autism caused by SATB2 is very rare, diseases in old age quite often involve the SATB2 gene being either over expressed or under expressed. As a result there is much more research on SATB2 than I expected. The current research into Glass Syndrome / SATB2-associated syndrome is mainly collecting data on those affected, rather than investigating therapies. There are some links later in this post, for those who are interested. The research into SA...