The Kynurenine Pathway in Autism and its modification using Sulforaphane or the probiotic Lactobacillus Plantarum 299v
A pathway to somewhere, hopefully Today’s post was prompted by our reader George’s observation that the probiotic Lactobacillus Plantarum 299v increased speech in his adult son. This widely available probiotic is commonly used to treat IBS (Irritable Bowel Syndrome) and I did mention it in a recent post about Eubiotics. Eubiotics for GI Dysfunction and some Autism Increased speech is a target for many people treating autism and this probiotic is known to be safely used long term - so it is interesting. Since I already had this probiotic at home, I made a trial and I observed a very similar effect to what happened several years ago when Monty started to use Sulforaphane / broccoli sprout powder. The effect of broccoli powder was a brief period of euphoria about 20 minutes later and a then a marked increase in verbalization. The effect on mood was seen by some other readers, but not the majority. I recall back then a very happy parent who was feedin...