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Propranolol, Autism and Sodium Ion Channels Nav1.1, Nav1.2, Nav1.3 and Nav1.5

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When writing this blog I frequently wonder what happened to all the very clever people; why are these full-time paid researchers often missing the obvious? Boy with severe headache and ASD, awaiting Propranolol The answer is, with a few notable exceptions (Catterall, Ben-Ari etc), the clever ones do not study autism, they study things that are much better defined, rare things like Angelman Syndrome and, recently, Pitt-Hopkins Syndrome.  These researchers seem much more rigorous.  For example:- David Sweatt (Pitt Hopkins) Pitt–Hopkins Syndrome: intellectual disability due to loss of TCF4-regulated gene transcription Edwin Weeber (Angelman syndrome) http://weeberlab.com/as.html So autism is left to what might be termed the Baron Cohen brigade. Propranolol Propranolol is a medication of the beta blocker type.  It is used to treat high blood pressure, a number of types of irregular heart rate , thyrotoxicosis , performance anxiety , and essential tremors .  It is used ...