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Showing posts with the label DMF

DMF for Mitochondrial Dysfunction in Autism and Friedreich's Ataxia?

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Yet more money was just donated to autism research. In 2017 the CEO of Broadcom gave $20 million to MIT and now he has given $20 million to Harvard, where he did his MBA. Time to boost Homer's mitochondria? I think philanthropists from the fast-moving IT sector should demand rather more from the slow-moving world of autism research.   I also think common sense is often more lacking than money. The US Government has also just announced $1.8 billion for autism research. Donald Trump authorized a five-year extension of the Autism Collaboration, Accountability, Research, Education and Support (CARES) Act. The 2014 act dedicated funds to children with autism spectrum disorder, but the new version includes adults.   Children with autism do indeed grow up to become adults with autism.   Today we look at further applications of DMF, which is a cheap chemical also sold as a very expensive drug. We learnt from Dr Kelley, from Johns Hopkins, that most regressive autism features mito...

DMF and MMF for Neuroprotection and Immunomodulation in MS, TBI, Parkinson’s and potentially much more

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DMF is an inexpensive chemical and was used to stop mould growing on sofas shipped from China to Europe, until it was banned as a skin irritant. It is also an expensive drug, sold by Biogen. DMF was discussed in an earlier post on ketones, because one of the anti-inflammatory effects of the ketone BHB can also be achieved using Dimethyl Fumarate (DMF). In the body DMF is converted to MMF by a chemical reaction with the body’s key antioxidant Glutathione (GSH). Surprisingly, DMF then goes on to improve GSH recycling and actually raise GSH levels. Ketones and Autism Part 3 - Niacin Receptor HCA2/GPR109A in Autism, Colonic Inflammation, Psoriasis and Multiple Sclerosis                         DMF is a very cheap chemical that has been sold as an extremely expensive drug, first in Germany to treat Psoriasis and later Multiple Sclerosis (MS). I did explain in an earlier post ho...