Gene Silencers and Enhancers in Autism; plus Epicatechin, MOCOS, Ferritin and Oxidative Stress (GR, GPx, GCL, GCLM)
The original idea of this blog was to try to keep complicated things as simple as possible, so at times things may get over-simplified. This post starts out simple and then gets rather involved in oxidative stress. When people think about genes, they are nearly always thinking about the “blueprints” that are encoded on your DNA. As it turns out only about 5% of your DNA is dedicated to this function; this 5% is contained in the exome . Much autism research is dedicated to finding faulty “blueprints” that might account for autism. There are now several hundred so called “autism genes”, where an error in the “blueprints”, means that the associated protein is not produced to its intended specification. We also have seen that genetic defects just lead to a possibility of something going wrong. A “faulty gene” creates the possibility of a specific dysfunction happening, it does not mean 100% that it will happen. Partial dysfunctions and partial deficiency...