PLT Test Blog

Today we consider another risk factor that may be contributing to the increase in prevalence of autism and it is about the father, for a change.   In the public's perception cannabis is a safe alternative way to treat all kinds of medical problems, many experts do not agree. Cannabis may Epigenetically Mark Men’s Sperm for Autism Fathers who use marijuana may be using it for two, suggests a study from Duke Medical Center. Although the study is small, encompassing just 24 men and 15 rats, it highlights a potential transgenerational effect of marijuana exposure—the passing on of sperm in which an autism-associated gene, DLGAP2, has accumulated extra epigenetic marks. The Duke scientists, led by Susan Murphy, PhD, associate professor of obstetrics and gynecology, identified significant hypomethylation at DLGAP2 in the sperm of men who used marijuana compared to controls. A similar observation was made in the sperm of rats exposed to tetrahydrocannabinol (THC) compared to controls...

I was spoilt for choice this week; which half-finished post to complete and publish?     The deciding factor was seeing just how interested people seem to be in cannabis.     It is the big thing at Autism conventions, currently. Italy is home to some unconventional medicine Today we see how you can target these receptors without the need to use any kind of cannabis.   I do spend time encouraging Monty’s 18-year-old big brother to avoid recreational drugs; so that is to declare my broader perspective on the issue. These drugs seem very popular among college students of every nationality, but according to my son particularly among those from countries where they cannot freely buy alcohol, like the US. In today’s post we go back to look at PEA ( Palmitoylethanolamide) which I proposed, and then rejected, as an autism therapy way back in 2014. PEA is widely used to treat neuropathic pain in Italy and Spain. PEA is a substance you already have in your body and it pla...