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Showing posts with the label Aggression

Pioglitazone for Autism and Specifically Summertime Raging and Verapamil-responsive Autism?

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  Adult-sized people with autism can cause property damage and much worse. I am told that summertime raging is a common problem encountered by neurologists, but it remains poorly understood and usually remains untreated. The most common worry for parents of toddlers diagnosed with severe autism is their lack of speech. By the time these children reach adulthood, the biggest worry for parents is often aggression and self-injury. Often it is the mother who faces the worst episodes of aggression, which is a really cruel turn of events. Aggression is usually not present in young children with autism, in some people it never develops, but in others it later becomes established as a learned behavior and then you are stuck with how to deal with it. One of my own therapy targets has long been to improve cognitive function; this can indeed be achieved and then you can improve important daily living skills (adaptive function). Some steps that you can take to improve cognition, and indee...

Self-Injurious Behavior (SIB) in Autism– if all else fails, why not ECT?

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  I did mention Electroconvulsive Therapy (ECT) in a recent post as a therapy for Self-Injurious Behavior (SIB) in autism and since there has been a review paper published very recently, it is the topic of today’s post. There was a previous post on this subject:- Electro Convulsive Therapy (ECT) and Cannabidiol (CBD) in Autism By coincidence, Mr Electric, Elon Musk, has just revealed that he has Asperger's Syndrome. I don't think he will be fitting ECT to his Tesla vehicles anytime soon.  ECT is likely only going to be used by those at the other extreme end of the autism spectrum, the ones who do not know was money is, let alone cryptocurrencies. There are many possible ways to treat someone who self-injures or indeed is aggressive towards others. From a psychiatric unit you might get various psychiatric drugs (antipsychotics etc), protective and restraining devices and in some cases Electroconvulsive Therapy (ECT). Some literature on ECT suggests that it is effective in almo...

Vasopressin, Oxytocin, the Lateral Septum, Aggression and Social Bonding, Autism gene NLGN3 and MNK inhibitors for reversing Fragile-X and likely more Autism

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  The Lateral Septum, in green, turns the volume  up or down in aggression Today’s post started by me checking for anything new in the research about the hormone Vasopressin and autism. I was surprised by just how much research continues to be published on the subject – no smoke without fire, perhaps. We also get another insight into how aggressive raging develops in the brain; we even have a photo. A novel therapy for Fragile-X is also thrown into the mix, due to a link to oxytocin. So, what is cooking in the research? The first thing to note is that you really do have to look at both Oxytocin and Vasopressin, because these two hormones are very closely related. We have previously looked at the autism gene NLGN3, this gene encodes the cute sounding neuroligin-3.   https://epiphanyasd.blogspot.com/search/label/neuroglin   The reason people with Fragile-X have autism is because they lack the protein FMRP ( Fragile X mental retardation protein). In healthy n...

Autism and the Police – challenging behaviors leading to restraint

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  Today’s post is about an issue that seems to cause a problem in some countries far more than others. While some people with mild autism (Asperger’s) may feel anxiety when dealing with the police, the big problem occurs when the police are called in to restrain someone with severe autism and particularly someone who is also non-verbal with MR/ID.   Most people with untreated severe autism actually have MR/ID, even if it was never diagnosed. It would never occur to me to call the police to restrain my own son, but in North America this is a regular occurrence.   It sometimes does not end well, often it was the parents who called the police, when it is not the parents it is likely to be the school. The research shows that most often the police in the US do successfully resolve the incident. I did ask my son’s assistant what she knows about the police dealing with aggressive autistic people. She knows lots of people with autism and parents. She initially did not understan...