PLT Test Blog

  62 clinical trials with Psilocybin are registered Today’s post is about treating a wide range of conditions that share neuroinflammation in common, by targeting the serotonin receptor 5-HT 2A . Severely disabling cluster headaches, that were seen as untreatable, have been resolved by monthly micro dosing with psilocybin. Psilocybin is a naturally occurring prodrug compound produced by more than 200 species of fungus, including magic mushrooms. Psilocybin is quickly converted by the body into Psilocin.   Psilocin Binding Profile Target Affinity Species   K i  (nM)   SERT 3,801.0 Human   5-HT 1A 567.4 Human   5-HT 1B 219.6 Human   5-HT 1D 36.4 Human   5-HT 1E 52.2 Human   5-HT 2A 107.2 Human   5...

  There are two closely related hormones, vasopressin and oxytocin, that have been extensively researched in autism.   With oxytocin you can modify social-bonding behavior. You can increase oxytocin in the brain either via a nasal spray containing oxytocin, or you can add a specific bacterium to your gut that triggers a signal to the brain to produce more of its own oxytocin.   The latter is my preferred method, because you can produce a mild long-lasting effect throughout the day. Oxytocin has a very short life and it does not cross the blood brain barrier. There is even a new study in the works that will compare these two methods of treating autism.   Probiotics and oxytocin nasal spray as neuro-social-behavioral interventions for patients with autism spectrum disorders: a pilot randomized controlled trial protocol Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impairments in social interaction and communication. Oxyt...