The Knudson Multiple Hit Hypothesis in Cancer, leading to the emerging Peter Multi-Mutation Matrix Theory of Autism
In Autism the more complicated research and emerging diagnostic tools seem mainly to relate to things like genes and CNVs ( Copy Number Variants ). To understand this in detail, a PhD in genetics might be helpful; but once you realize that nobody fully understands this emerging area of science, we may still be able to draw some usable insights, that have not been noticed by the autism research community. The focus of research is on cancer; autism remains in a backwater. However, what research there is on autism and genetics does seem to show rather more overlap with the mechanisms and pathways seen as being behind cancer than you might have expected. This, combined with the very odd sounding finding by that Nobel Laureate at MIT, that neither cancer nor autism can develop without the presence of a substance called PAK1, makes me interested to look at the cancer research. Then you notice after only a few minutes of research, that there are numerous instanc...