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Showing posts with the label ESP

Dr Dolittle, Autism and the Broccoli Sprouts

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In the Dr Dolittle books and subsequent films, a man develops the power to communicate with animals.  It seems that one effect of broccoli sprout powder (and we assume Sulforaphane), in autism,  is an urge to talk, not only to humans, but also to animals. Monty, aged 11 with ASD, took his first dose of 2.5ml of broccoli powder ( Supersprouts brand from Australia) and after about half an hour developed euphoria.  The laughter later subsided and throughout the day he was very talkative.  This was relevant speech and not repeating things he had heard previously.  Other than the euphoria, which is the word chosen by elder brother Ted, a nice development was the desire to communicate with the animal world. After a visit to his favourite ice cream shop, he looked up and saw the big railway bridge. “Bye bye railway station” commented Monty.  Walking up the hill we first passed a kitten, playing by the verge, “Hello baby kitten! Bye bye baby kitten!”  Then a ...

Sulforaphane, Epithiospecifier Proteins (ESP) or just Sulforadex for Autism

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    One reader of the last post on Sulforaphane raised the issue of whether she should cook her broccoli sprouts, to optimize her autism therapy. This seemed a bit strange, since even the researchers at Johns Hopkins are eating their sprouts raw.   She does have a valid point.  It seems that while sprouts have large amounts of glucoraphanin  and the required enzyme myrosinase, they also have something called Epithiospecifier Protein (ESP).  If there is much ESP present, instead of Sulforaphane you get a very similar compound called Sulforaphane Nitrile.  You can see that the “S” has been replaced by an “N”. All is not lost, for those of you with sprouts growing in the kitchen. Further research showed that the concentration of ESP in the sprouts peaks on the second day and that by day 5 has dropped dramatically. It was also showed that raising the temperature of the sprouts to 60 degrees Celsius deactivated the ESP.  Heating Broccoli florets much...