GABA A Receptors in Autism – How and Why to Modulate Them
This post will get complicated, since it will look at many aspects of the GABA A receptor, rather than just a small fraction that usually appear in the individual pieces of the scientific literature. It was prompted by comments I have received from regular readers, regarding Bumetanide, Clonazepam, epilepsy and whether there might be alternatives with the same effect. So it is really intended to answer some complex issues. There are some new interesting facts/observations that may be of wider interest, just skip the parts that too involved. Regarding today’s picture, most readers of this blog are female and by the way, while the US is the most common location by far, a surprisingly high number of page views come from France, Hong Kong, South Africa and Poland. GABA We have seen that GABA is one of the brain's most important neurotransmitters and we know that various forms of GABA dysfunction are associated with autism, epilepsy and indeed schizophrenia. One re...