T helper cells in Autism - TH1 TH2 & TH17
Today’s post is about another complex and still emerging subject. It should really be earlier in this blog. There are lots of papers highlighted for those who like the details. The papers written by the autism researchers are generally much simpler to read than those by the mainstream researchers. First some biology:- Source: https://www.hindawi.com/journals/mi/2013/963748/fig1/ Differentiation of naïve T helper cells into particular subsets. T helper lymphocytes leaving the thymus (naïve or Th0) are not yet fully differentiated to perform their specific functions in peripheral lymphoid tissues. They are endowed of these properties in the process of their interactions with dendritic cells (DCs) that engulf, process, and present antigens to them. DCs produce different cytokines. If DCs produce IL-12, naïve T cells polarise into the Th1 subset If DCS produce IL-4 into the Th2 subset if DCs synthesise IL-6, naï...