Autism, Schizophrenia, MR, 5 Overlapping Genes and Epigenetic Dysfunction
In a recent post I raised the issue of maybe we should be looking at the schizophrenia research, given that the condition appears very closely related to ASD. Then I got rather side tracked by MR (Mental Retardation), now known as Intellectual Disability, in polite society. Since schizophrenia is adult-onset, I thought it might attract some serious research; indeed it does. It turns out there may have been more sense than you thought, in my making “connections” between autism, schizophrenia and MR. A striking study has just been published from Trinity College, Dublin. It draws these three conditions together using genes and makes a remarkable conclusion regarding epigenetics. Epigenetic change has already been highlighted as a key process behind the development of autism. The full paper is not openly available, but below is the abstract and here is a press release from the University . De novo mutations in schizophrenia implicate chr...