Immunomodulatory Therapy in Autism - Potassium Channel Kv1.3, Parasitic Worms, and their ShK–related peptides
Regular readers of this post will know that I believe that Immunomodulatory therapy has great promise for treating various subtypes of autism. In effect, I want to bring the over-activated immune system back under control. Two methods that appeal are:- · The steroid, Prednisone, because it is cheap and though it has side effects, they are very well understood. It also has been shown to be effective in autism and related conditions like PANDAS and Landau - Kleffner syndrome (LKS) · Parasitic worms appeal because they are known to have beneficial effect in many auto-immune conditions ranging from arthritis to autism, but nobody really understood why. Until now. This post is about the worms and recent research which has established that it is likely that they work by blocking the potassium channel Kv1.3. You will have noted that this blog keeps going on about ion channel dysfunction...