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Showing posts with the label Immune disorder

Immunomodulatory Therapy in Autism - Potassium Channel Kv1.3, Parasitic Worms, and their ShK–related peptides

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Regular readers of this post will know that I believe that Immunomodulatory therapy has great promise for treating various subtypes of autism.   In effect, I want to bring the over-activated immune system back under control.   Two methods that appeal are:- ·         The steroid, Prednisone, because it is cheap and though it has side effects, they are very well understood. It also has been shown to be effective in autism and related conditions like PANDAS and Landau - Kleffner syndrome (LKS) ·         Parasitic worms appeal because they are known to have beneficial effect in many auto-immune conditions ranging from arthritis to autism, but nobody really understood why.   Until now. This post is about the worms and recent research which has established that it is likely that they work by blocking the potassium channel Kv1.3. You will have noted that this blog keeps going on about ion channel dysfunction...

Angelina Jolie or Destiny’s Child?

At the time of writing this post Angelina Jolie’s aunt has succumbed to the same cancer that killed Angelina’s mother and she announced that she also carried the same defective gene.   She opted to take pre-emptive action and, in effect, cheat a nasty early death from breast or ovarian cancer. I have read so much research into autism, that it is pretty clear to me, that you could calculate an Autism Risk Factor (ARF) for prospective parents, if you really wanted to.   Would you really want to?   I expect those with direct experience of autism might be in favour, the others probably would not even bother to answer the question.  Since few truly autistic people have children, it is really more of a question for their siblings; do they want Destiny’s Child? It may sound depressing, or something to do with eugenics, but actually it does not have to be.   I am not suggesting the sort of genetic and chromosome testing that is already routinely done for conditions like...