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Showing posts from February, 2019

Who lives in Libya? And Raising the level of BHB in your blood.

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Today’s post is mainly about some “home-research” that was sent to me by a company that sold me C8 oil (caprylic acid MCT oil). It is not peer-reviewed research, but it is a well thought out home experiment measuring the level of the ketone BHB in the blood of two healthy young adults testing a range of commercially available products. It is important to note that BHB was measured in blood and not urine, which is a big plus for the experiment. Dr D’Agostino’s starting dose First, a recap of where we started a few months ago in this blog. One of the leading ketone researchers is Dr D’Agostino and his suggested starting dose on ketone supplements is 10 ml of Ketoforce and 10ml of C8/caprylic acid. We saw in earlier posts that the amount of BHB produced by taking C8 is highly dependent on whether it is taken with food. Taken on an empty stomach resulted in more BHB in the bloodstream. 10 ml of KetoForce contains 4g of BHB along with 500mg of sodium and 500mg of potassium. BHB salts and BH...

Clemastine and Depression – Myelin, Microglia or Both? Microglia in Psychiatry, Plus LPC EPA and LPC DHA as promising future therapies

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Nibbling on Neurons – This is synaptic pruning Microglia (red) "nibble" a bit of filopodia (green), the membranous protrusions found primarily on dendritic stretches of developing neurons. Video from Weinhard, et al., Nature Communications, " Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction ," Today it is the post anticipated by Valentia in Uruguay, where it is currently hot and sunny. For Roger it is still winter and he may not be a fan today’s deep dive into the science, but I think he has already got the message about Clemastine’s potential for myelination, including, and importantly for him, in the peripheral nervous system (i.e. for myelination outside the brain).  If my posts get too complicated just skip down to the conclusion. I do go a little off-topic looking at EPA and DHA. We also take a deep look at microglia in psychiatric disorders. Today we see how Clemastine’s benefit in some people may be related to its effe...