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Showing posts from March, 2019

Improving Myelination through Social Interaction and more on Clemastine

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Since anecdotal evidence is beginning to support this blog’s suggestion that pro-myelinating therapy might be beneficial in autism, particularly improving human adaptive behaviour, I will continue to highlight further supporting research. Improving Jerry’s Brain Myelination - Hard without Tom Today’s main paper shows how social intervention can also be used as a pro-myelinating therapy (in mice, like Jerry). I found the research interesting, but I think most parents would opt for a pill as a short cut. The study looked at the effect of rearing an autistic mouse with social mice.  The autistic mouse shares the myelin defects of autistic humans. The research interestingly shows that it is the social interaction only after weening that has an impact on myelination. So in the human equivalent of this research, it is not interactions with Mum/Mom that matter most, it is interactions with toddler peers. So make sure your toddler with autism hangs out with bubbly neuro-typical toddlers, ...

PEA (Palmitoylethanolamide) Therapy for Autism? Targeting CB1 and CB2 without the need for Cannabis, plus PPARα and Microbiome changes

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I was spoilt for choice this week; which half-finished post to complete and publish?     The deciding factor was seeing just how interested people seem to be in cannabis.     It is the big thing at Autism conventions, currently. Italy is home to some unconventional medicine Today we see how you can target these receptors without the need to use any kind of cannabis.   I do spend time encouraging Monty’s 18-year-old big brother to avoid recreational drugs; so that is to declare my broader perspective on the issue. These drugs seem very popular among college students of every nationality, but according to my son particularly among those from countries where they cannot freely buy alcohol, like the US. In today’s post we go back to look at PEA ( Palmitoylethanolamide) which I proposed, and then rejected, as an autism therapy way back in 2014. PEA is widely used to treat neuropathic pain in Italy and Spain. PEA is a substance you already have in your body and it pla...