PLT Test Blog

Dr Karun Singh    This is a Guest Post by our reader AJ McMaster University Autism iPS Research Study First, a very big thank you to Peter for kindly offering to allow me to write this guest post. It is with great excitement that I am announcing the launch of what I believe is one of the most promising research projects in autism today – McMaster University’s Autism iPS Research Study.   In fact, I have been given the great privilege of helping McMaster University raise funds and awareness for this incredible endeavor. For those of you that aren’t familiar with McMaster University, it is Canada’s most research-intensive University, located in Hamilton, Ontario (just west of Toronto). What is the McMaster University Autism iPS Research Study? This research is being led by Dr. Karun Singh at McMaster University. You can learn more about Dr. Singh and his research at   https://sccri.mcmaster.ca/people/karun-singh .   The intent of this research is to study reprogra...

This is not a summary of the recent conference I attended in London, it is just the impressions I left with, which will be very different to those of the delegates and the other speakers. Hopefully I do not upset too many people. Here is information on the conference and PDF versions of the two presentations I gave. This is the only autism event I have ever attended, other than a discussion over lunch at a university reunion where someone organised a meeting for those from our year with an interest in autism. Other than that, I have really only ever met a handful of autism parents face to face. I did meet our reader Petra in Thessaloniki a few years ago.   As expected, Petra is a very nice person in reality and not just in the comments on this blog This weekend I met face to face with Agnieszka, Natasa who comments frequently and helps run the Think Autism charity in the UK, as well as many others who comment less frequently. I met my first MAPS-type doctor, Richard Frye and had a ...

Azosemide  C 12 H 11 ClN 6 O 2 S 2    Source: https://pubchem.ncbi.nlm.nih.gov/compound/azosemide Today’s post may be of interest to those already using bumetanide for autism and for those considering doing so .  It does go into the details, because they really do matter and does assume some prior knowledge from earlier posts. There has been a very thorough new paper published by a group at Johns Hopkins:- Off-Label Use of Bumetanide for Brain Disorders: An Overview It does cover all the usual issues and raises some points that have not been covered yet in this blog.   One point is treating autism prenatally. This issue was studied twice in rats, and the recent study was sent to me by Dr Ben Ari.   Short term treatment during pregnancy produced a permanent benefit. Maternal bumetanide treatment prevents the overgrowth in the VPA condition              Brief maternal administration of bumetanide before birth restores low ...