PLT Test Blog

Today’s post is really for the regular readers of this blog who are interested in the GABA switch and Bumetanide. It is not light reading.  We see how advanced some Taiwanese researchers are in their understanding of GABA A dysfunctions in Huntington’s Disease. Taipei 101, briefly the world’s tallest building It is an excellent paper and much of it is applicable to autism. There are some omissions, but you will struggle to find a more complete paper. They even go into the detail of altered the sub-unit expression of GABA A receptors that occurs as the disease progresses. I think that correcting sub-unit miss-expression has great potential in treating some autism. Huntington’s is an inherited brain disorder that first manifests itself around the age of 40 and then progresses for the next 15 to 20 years. Much autism is present prior to birth but there is a progression that occurs as the brain develops in early childhood. Some people do seem to be entirely typical at birth and only...

The Great Wall of China, two hours north of Beijing Monty, now aged 15 with ASD, continued his travels recently with an Easter visit to China. Long haul travel can be much more demanding than shorter trips because of the change in time zone and simply the fact that you are stuck on the plane for such a long time. Many people with autism, and indeed Asperger’s, have problems with air travel, while some other people even with severe autism have no issues whatsoever.   Some people with severe autism never go on holiday, travel being such a problem.   Some people repeat the same holiday every year.   It does not really follow any pattern. One issue I came across at the recent conference in London was that some people cannot even consider a far-away medical specialist or enroll in a clinical trial, due the travel required.   But what to do if the autism doctor does not make house calls? Some people do take their child thousands of miles to see a specialist, but many...