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Showing posts from June, 2020

P-Cresol, like Propionic acid – a cause of Transitory Autism for some and a further burden for others

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Today’s post has two themes, one relates to Transitory Autism, where a toddler with autism appears to “grow out” of the condition and the other is another substance produced in the gut, like we saw earlier with Propionic acid, that can produce “autism”.    Increased intestinal transit time and bacteria produce P-Cresol If your gut produces a lot of propionic acid, instead of butyric acid, you can appear to have autism. Today we see that producing too much P-Cresol in your gut produces symptoms of autism. I suspect in most cases P-Cresol is making severe autism worse, rather than making a neurologically healthy, but likely constipated, person exhibit autism. Elevated P-Cresol is associated with increased intestinal transit time and not Clostridium type bacteria.   We know that elevated P-Cresol is reduced after oral supplementation with oligofructose-enriched inulin.   It is suggested that certain probiotic bacteria might also lower P-Cresol.   A microbiota trans...