Posts

Autism Polypill Version 5

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Agnieszka's KetoForce and C8 are new additions, last time it was Tyler's Agmatine as additions to the  Full Polypill I recently updated my autism Polypill. It is now the fifth version, so it is becoming ever more personalized to one specific case of autism.   I added caprylic acid C8 and KetoForce Beta Hydroxybutyrate. The full Polypill version 5 is here:    https://epiphanyasd.blogspot.com/p/polypill-for-autism.html I do feel that I am getting near the final version. I already am pretty sure what is going to be added in the sixth version. There are one or two potentially clever ideas in this blog that I have not yet developed. After my first year of autism research my doctor mother thought the result was good enough to stop, but I persevered and some further improvement did come. She was supportive of the concept but rather surprised it was possible. I think I have now achieved most of what is possible, which took an additional five years. Having recently been revi...

A 15 year Longitudinal Study of French Autism and a look at Early Diagnoses of US Autism that Resolved

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Today’s post is all about what to expect in the future; it covers a detailed look at 2 different studies that I think are best considered in a single post. Forewarned is forearmed. How high to set the bar? In a recent post I highlighted the need for long term (longitudinal) studies showing what happened to people diagnosed with autism back in the 1990s in California and New York, when an autism diagnosis was much more meaningful and yet early intervention was already available. We could then see what the outcome was 20 years after diagnosis and this might help parents decide their own autism strategies for today. I was encouraged to subsequently come across today’s study from France that traces the progress made over 15 years by a group diagnosed with autism.   I also include my take on a popular recent study that showed what “Optimal Outcome” looks like in American autism, but that looks just over a 4 year period. Don’t raise your hopes. All this leads to the practical questio...

Improving Myelination through Social Interaction and more on Clemastine

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Since anecdotal evidence is beginning to support this blog’s suggestion that pro-myelinating therapy might be beneficial in autism, particularly improving human adaptive behaviour, I will continue to highlight further supporting research. Improving Jerry’s Brain Myelination - Hard without Tom Today’s main paper shows how social intervention can also be used as a pro-myelinating therapy (in mice, like Jerry). I found the research interesting, but I think most parents would opt for a pill as a short cut. The study looked at the effect of rearing an autistic mouse with social mice.  The autistic mouse shares the myelin defects of autistic humans. The research interestingly shows that it is the social interaction only after weening that has an impact on myelination. So in the human equivalent of this research, it is not interactions with Mum/Mom that matter most, it is interactions with toddler peers. So make sure your toddler with autism hangs out with bubbly neuro-typical toddlers, ...