PLT Test Blog

Mardin is a city in Southeastern Turkey on the overland Silk Road (in red) Today’s post does not have any science. Just after the new year Monty went to southeast Turkey to visit Mardin, an old city that was on the Silk Road linking Asia to Europe and then to see more of Istanbul. Travel can be difficult for people with autism, even fully verbal people with above average IQ.   Some people with Asperger’s refuse to fly because they fear the plane is going to crash.   Exaggerations and distortions of normal perception are actually examples of psychotic behavior, in the extreme these are the "positive" symptoms of schizophrenia.   This loss of touch with reality does feature to varying degrees in some Aspies. Monty started to fly while still a baby and, in spite of a few glitches along the way, has become quite a seasoned traveller for a 16 year old.    The latest trip was a little off the beaten track for western tourists, in fact we did not see any other western ...

Piperine/Pepper             Resveratrol/Red wine          Sunitinib/Sutent    This post is all about lowering chloride within neurons, by increasing the expression of the transporter that lets it leave, called KCC2. Today’s post is one I never finished writing from last year; I looked up the price of Sutent/Sunitinib and then I remembered why. It does again highlight how cancer drugs, when they become cheap generics, will provide interesting options for autism treatment. It also shows again how Rett Syndrome is getting attention from researchers. It also highlights that really clever Americans are looking for bumetanide alternatives, in the false belief that bumetanide has troubling side effects that cannot be managed/mitigated. The study is by some clever guys in Cambridge Massachusetts. Another group of clever guys from MIT burned through $40 million dollars a few years ago trying to develop R-Baclofen for Fragile-X...