Posts

Fenamates (Diclofenac, Ponstan etc): certainly for Alzheimer’s, maybe some Epilepsy, but Autism? I’m Impressed!

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  Some readers of this blog are interested in the potential of mefenamic acid (MFA), sold as Ponstan, to treat autism. There is a lack of evidence currently.   On the other hand, the evidence looks pretty overwhelming in the case of this class of drug to treat Alzheimer’s, hence today’s post. If you have a case of epilepsy at home, you can follow up on that loose end I left. I also introduce MFA as a therapy for sound sensitivity and Misophonia. It was pretty impressive in the case of Monty, aged 18 with ASD.   The highlights are:   ·         Fenamate NSAIDs reduce the incidence of Alzheimer’s ·         Fenamate NSAIDs delay the progression of those already with Alzheimer’s ·         Acetaminophen /Paracetamol worsens the progression of Alzheimer’s ·         Low dose aspirin is chemoprotective, as well as reducing blood ...

SEECA 2022 - Autism Conference in Belgrade June 2-4

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  Our reader Tatjana has been busy organizing an autism conference in Belgrade, for doctors and parents.   It is called the South-East European Conference on Autism (SEECA) and takes place June 2 - 4. Researchers and clinicians from around the world are coming to speak, many of whom have been mentioned previously in this blog. Dr Frye of folate and mitochondrial disorders, Dr Lemmonier with Bumetanide, Dr Krigsman the gastroenterologist, Dr Adams with FMT, Dr Antonucci with an overview of the many interventions that he finds useful. Plus others I have not previously mentioned in my blog, who will talk about PANS/PANDAS, Suramin, Stem Cell Treatment and more. Tatjana has been busy. Click on the link below to read all about it.   SEECA Conference   You can attend the conference online, if you are not able to travel to Belgrade.

From a SWAN to Chopra-Amiel-Gordon Syndrome and the emergence of “-like” syndromes, CNTNAP2 etc

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  SWAN (Syndrome Without A Name)   Today’s post is complicated, it is aimed at people who: ·         are interested in genetic testing for autism   ·         are affected by miss-expression of the genes:- ·         ANKRD17 ·         TCF4 ·         CNTNAP2 ·         NRXN1   It is one of those posts that could go on forever; the more you dig, the more you uncover and you wonder why other people (salaried researchers) are not doing this. Today’s post is mainly about a gene called ANKRD17, but it does highlight more general principles about those genetic testing results, some parents strive to obtain.   It does look at downstream effects of Pitt Hopkins Syndrome and “Pitt Hopkins-like Syndrome”, which likely merge into mainstream autism. Many single ...